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Moon Jung's father comes to the hospital, and he says something unexpected to Woo Jin. And Woo Jin hears about the shocking truth about Woo Jin's father from Moon Jung. Eun Jae gets a call from the main hospital to return. Director Yeo says goodbye to people at Doldam Hospital. Min Kook leaves after the incident, but Dr. Kim tries to bring him back.

Dr. Do suddenly visits Doldam Hospital and is on bad terms with Dr. Woo Jin. The main hospital organizes and sends a fact-finding committee to Doldam to investigate the table death which occurred during the procedure led by Director Park. Nurse Joo suspects the relationship between Ah Reum and In Beom as they look very close to each other.

Woo Jin is threatened by the creditors to move to another hospital. Min Kook finally performs surgery on his VIP patient. Director Yeo is transferred to the emergency room unconscious, and Dr. Kim is in agony as Director Yeo signed the Do Not Resuscitate form.

Min Kook tries to operate on his VIP patient, but Dr. Shim strongly goes against him. And Ho Jun is stuck in between them. Woo Jin keeps bothering Min Kook and his team with emergency patients and finally gets to operate once again. Woo Jin is taken by the loan sharks, and he sees Hyun Jun. Hyun Jun threatens him to sign a contract.

Hyun Jun visits Doldam Hospital to meet Woo Jin. He used to be the doctor of Samjin Hospital, where Woo Jin was. Hyun Jun pokes around people and trying to scatter them. Dr. Kim finally decides to take action and fight against Dr. Park. After Woo Jin found out that it was Eun Jae's brother who made a mistake and kept it secret to the patient, Eun Jae also finds out about the truth.

Nurse Oh gets furious at Dr. Kim because he wouldn't listen. After Dr. Kim collapsed, everyone is worried about him. Woo Jin suggests Dr. Kim receives surgery on his wrist. Director Park fires Dr. Nam and assigns his people at the ER to stop accepting trauma patients. During surgery, Woo Jin finds out that a doctor who performed an operation on his patient made a mistake but didn't inform the patient.

Min Kook arrives at the accident scene. Dr. Kim's and Min Kook's opinions on how to treat patients conflict. Woo Jin spots that Dr. Kim is also hurt, but Dr. Kim won't rest and get treated. A police officer comes to the hospital and asks Ah Reum to have a word about the rape victim.

Ho Jun senses something is going on between Woo Jin and Eun Jae. Woo Jin notices Dr. Kim has a problem with his arm. Min Guk gathers doctors and announces to change the system of Doldam Hospital. But Myung Shim gets furious and stands against him. Dr. Kim takes a bus to get back to the hospital, but the bus rolls over.

Eun Jae loses her confidence from the domestic violence incident, and Dr. Kim cheers her up by telling her that it isn't her fault. A paramedic comes into the ER, unconscious, and she is declared as brain-dead in the end. And the condition of a patient from prison gets worse. Eun Jae finds out that Woo Jin had lost his parents when he was young.

Nurse Oh finds out that Director Yeo has lung cancer. A loan shark comes to the hospital and makes a scene to embarrass Woo Jin. Eun Jae feels uncomfortable for causing trouble, so she decides to apologize. Doldam hospital gets a call, and Dr. Kim and Min Guk fiercely conflict over a patient from prison.

A detective with a gunshot wound and a gang boss with a stab wound come into the ER at the same time. Both of them want Dr. Kim to do the operation, but that's just impossible. Meanwhile, Nurse Oh finds a note at the director's office and notices something is going on with the director. Eun Jae finds a beaten wife in the bathroom and confronts her husband, but something unexpected happens.

Friday is the busiest day as a lot of patients swarm in Doldam Hospital. Eun Jae still finds it hard to perform surgical operations herself. A girl patient who suffers from drug poisoning because of her father's joint family suicidal attempt reminds Woo Jin of a painful memory from his childhood. And the staff of Doldam Hospital resents after hearing a rumor that there will be a new director.

Min Kook asks Woo Jin questions about the primary surgery that Dr. Kim operated on, and Woo Jin hesitates to answer them. The director of Doldam Hospital comes back to the hospital, and Ah Reum greets him. Eun Jae gets furious at Woo Jin for taking away her opportunity to be in the second operation with Min Kook. And Doldam Hospital is on the verge of being sued for malpractice.

Dr. Kim chooses the extreme method to save Minister Ryu. After Dr. Kim manages to bring Minister Ryu back to life, Min Kook starts doubting Dr. Kim's real intention and skills. After Min Kook announces the Minister's condition to the press, Dr. Kim just doesn't seem to care. Eun Jae asks Woo Jin to attend the second surgery, but he refuses.

Dr. Kim gets disappointed at Woo Jin and tells him to go back. But Woo Jin asks Dr. Kim for one more chance, and Dr. Kim gives Woo Jin a week of grace period to prove himself. Meanwhile, an important figure comes into the emergency room of Doldam Hospital. Do Yoon Wan, the chairman of the Geosan University Foundation, figures out the news and begins to work out his scheme.

As Doldam Hospital suffers from a lack of doctors, Kim Sa Bu visits the main hospital to ask to send young doctors to him and runs into CS fellow Cha Eun Jae and GS fellow Seo Woo Jin. Seo Woo Jin is ostracized by other doctors because he had done whistleblowing on other doctors' corruption and malpractice. On the other hand, Cha Eun Jae always takes a tranquilizer before operations due to her operation fright.